Dressings Ī 2018 Cochrane review found that silver-containing dressings may increase the probability of healing for venous leg ulcers. The US Food and Drug Administration (FDA) approved a number of topical preparations of silver sulfadiazine for treatment of second-degree and third-degree burns. It is on the World Health Organization's List of Essential Medicines. However systemic reviews in 2014, 20 concluded that more modern treatments, both with and without silver, show better results for wound healing and infection-prevention than silver sulfadiazine, and therefore SSD is no longer generally recommended. It was discovered in the 1960s, and was the standard topical antimicrobial for burn wounds for decades. Silver sulfadiazine (SSD) is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. Thus dead bacteria may be the source of silver that may kill additional bacteria. Silver, used as a topical antiseptic, is incorporated by bacteria it kills. The antibacterial action of electrodes coated with silver nanostructures is greatly improved in the presence of an electric field. Applying an electric current across silver electrodes enhances antibiotic action at the anode, likely due to the release of silver into the bacterial culture. The antibacterial action of silver has long been known to be enhanced by the presence of an electric field. ) to irreversibly damage key enzyme systems in the cell membranes of pathogens. The effectiveness of silver compounds as an antiseptic is based on the ability of the biologically active silver ion ( Ag + The antibacterial action of silver is dependent on the silver ion. Silver and most silver compounds have an oligodynamic effect and are toxic for bacteria, algae, and fungi in vitro. Alternative medicine products such as colloidal silver are not safe or effective. Silver generally has low toxicity, and minimal risk is expected when silver is used in approved medical applications. There is tentative evidence that using silver-alloy indwelling catheters for short-term catheterizing will reduce the risk of catheter-acquired urinary tract infections. The limited evidence available shows that silver coatings on endotracheal breathing tubes may reduce the incidence of ventilator-associated pneumonia. Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections. Not long after Paul Karason came to suffer from argyria, the FDA banned the use of colloidal silver in oral drugs.The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. And that's when it hit me,” Papa Smurf explained in an interview in 2008.ĭespite the fact that he stopped taking the dietary supplements, the man remained blue for the rest of his life. “And he looks at me and he says, ‘What have you got on your face?’ ‘I don't have anything on my face!’ He says, ‘Well, it looks like you've got camouflage makeup on or something.’ And by golly, he came in and he was very fair-skinned, as I used to be. The change took place so gradually that Paul Karason did not even realize something was off until a friend of his paid him a visit. However, in just a few months, the silver also turned his skin blue. And the next thing I knew, it was just gone,” Paul Karason told the press back in 2008. I had arthritis in my shoulders so bad I couldn't pull a T-shirt off. “The acid reflux problem I'd been having just went away completely. silver particles suspended in liquid) in an attempt to treat his acid reflux and arthritis.īy the looks of it, the colloidal silver proved quite effective in terms of ridding the man of said health problems. Thus, about 15 years ago, the man started taking colloidal silver (i.e. Doctors were unable to revive him.ĪBC News tells us that Papa Smurf owed his odd skin color to a rare medical condition known as argyria, or silver poisoning. While undergoing treatment for said condition, he suffered a heart attack. Information shared with the public says that the man had been admitted to hospital to be treated for pneumonia. 62-year-old Paul Karason, otherwise known as the real-life blue man or Papa Smurf, passed away at a hospital in Washington earlier this week.
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